Papa John’s Pepperoni Pizza Original Crust (Large)
A Pepperoni Pizza from Papa John’s is smothered in a signature sauce and covered in real mozzarella cheese and lots of pepperoni.
One slice form a large pepperoni pizza has 320 calories, 13 grams of fat, 38 grams of carbohydrates, and 12 grams of protein.
Read this guide for a comprehensive overview of the nutrition facts, calories, and ingredients in Papa John’s Pepperoni Pizza.
Pepperoni Pizza Nutritional Information
Unless otherwise noted, the nutritional information in this guide is based on a single serving measured as One Slice from a Large Original Crust Pepperoni Pizza that is cut into 8 slices.
Serving Size 1 Slice (Large Pizza)
Calories
320% Daily Value
saturated fat
30%HIGH
sodium
35%HIGH
CHOLESTEROL
10%MED
%DV based on 2,000 calorie daily diet
Calories
Each serving from a large pizza contains 320 Calories.
Here’s the amount of calories in one slice from fat, carbs, and protein.
The highest proportion of the total calories is derived from carbohydrates. Dietary fat makes up 38% of the total calories, and the remaining 16% is from protein.
The amount of calories per macronutrient above is a rounded estimate based on the nutrition facts provided by Papa John’s. Calories may vary by location or as a result of how the pizza is prepared.
Calories Vary by Size Pizza
One serving is measured as a single slice. The calories and nutrition per slice will vary based on the size of the pizza and the number of slices cut.
Here is a quick summary of the total calories per slice from each size pizza available at Papa John’s pizzeria.
Total Fat
There are 13 grams of total fat, including 6 grams of saturated fat in each serving.
For your reference, U.S. FDA states that a nutrient with 20% or greater daily value (% DV) per serving is considered high.
Based on that general guidance, the amount of saturated fat in the pepperoni pizza is considered high. One serving has a 30% daily value (based on a 2,000 calorie diet).
SUMMARY OF DIETARY FAT PER SERVING
Sodium
Likewise, the amount of sodium per serving is considered high. Each slice contains 810 milligrams of sodium, which is a 35% DV.
With 810mg sodium per slice and 8 slices per large pizza, a whole pepperoni pizza has 6,480 milligrams of sodium.
Here is the nutrition facts label for Papa John’s Original Crust Pepperoni Pizza.
Nutrition Summary
Serving Size 1 Slice (Large Pizza)
CALORIES
320TOTAL FAT
13g(17%DV)
CARBOHYDRATES
38g(14%DV)
PROTEIN
12gSaturated Fat | 6g (30%DV) |
Trans Fat | 0g |
Cholesterol | 30mg (10%DV) |
Sodium | 810mg (35%DV) |
Dietary Fiber | 2g (7%DV) |
Total Sugars | 5g |
%DV (Percent Daily Values) are based on a 2,000 calorie diet. Calorie needs vary and your daily value may be higher or lower. Provided for informational purposes only. Consult with your physician for dietary or healthcare advice.
Ingredients and Allergens in Pepperoni Pizza
Ingredients
Here are the ingredients in Papa John’s pepperoni pizza.
Original Crust
Ingredients:Unbleached Enriched Wheat Flour, Water, Sugar, Soybean Oil, Salt, Yeast.
Cheese
Ingredients:Part-Skim Mozzarella Cheese (Pasteurized Milk, Cultures, Salt, Enzymes), Modified Food Starch, Sugarcane Fiber, Whey Protein Concentrate, Sodium Citrate.
Pepperoni
Ingredients:Pork, Beef, Salt, Spices, Natural Flavoring, Dextrose, Lactic Acid Starter Culture, Oleoresin of Paprika, Natural Hickory Smoke Flavoring, Sodium Nitrite.
Pizza Sauce
Ingredients:Fresh Vine-Ripened Tomatoes (packed from vine to can in same day), Sunflower Oil, Sugar, Salt, Garlic, Spices, Extra Virgin Olive Oil, and Citric Acid (for freshness).
What is Lactic Acid Starter Culture?
Also known as lactic acid bacteria, a lactic acid starter culture (used in the pepperoni) is a living microorganism that consumes sugar in food and produces lactic acid.
Lactic acid bacteria and coagulase-negative staphylococci may be used as starter cultures. Certain yeasts and molds may also be used.
It’s used in cured meats to promote fermentation and to protect the food from becoming contaminated with pathogens. Starters may also be used to shorten ripening times.
Brief Definitions of Select Ingredients
Allergens
The original crust pepperoni pizza at Papa John’s is made with ingredients that contain milk and wheat.

Ingredients, allergens, and nutrition facts are based on available information as of the date this article was published and/or updated. Restaurants and food manufacturers may change their recipes without notice. Check directly with the food provider for the most accurate and up-to-date information. NutritionandIngredients.com does not provide health or wellness advice or dietary recommendations. Our aim is to research commercially processed food and publish articles for informational purposes only. Unless otherwise stated, % Daily Value is based on 2,000 calories per day, but calorie needs vary by individual. Always consult your physician for any healthcare or dietary advice.
Nutrition facts, ingredients, allergens: Papa John’s